For recent years, application of biopolymer as an edible film has received growing interest because of their advantages including environmental friendly and non-toxic food barrier property. However, the mechanical and barrier properties of biopolymer film are poor compared to conventional synthetic film. Incorporation of nanofiller into biopolymer matrix may become a novel innovation in food packaging industry. Nano-sized fillers provide large contact surface area that favors strong matrix-filler interaction compared to micron-sized fillers. They also provide other desired functions of active food packaging film including antimicrobial agent, biosensor, and oxygen scavengers. The objective of this paper is to provide a general review on the potential edible nanofiller, preparation, properties and performances as well as application of nanofiller into edible film