Nursing Performance independent to internal and external of the hospital, is measured based on personal balanced scorecard so as to measure the quality of nursing services. The fact that is evident from this study is that majority of nurses expressed job dissatisfaction, and there is no career development system for them. This study aims to understand the relation between nurse performance based on Personal balanced scorecard and job satisfaction of nurses in inpatient units of Islam Ibnu Sina Hospital Bukittinggi. This research method is descriptive analytic with cross sectional approach. A sample of 72 respondents participated in the study. The research instrument used questionnaires. Chisquare test and multivariate logistic test were used for data analysis. The result showed a significant relationship between the performance of nurses based on the financial perspective, internal business perspective, customers’ perspective, growth and development perspective with job satisfaction of nurses (p values <0.05). The most dominant variable is the performance of financial perspective. It is suggested to the leaders of the hospital to formulate performance indicators of nurse so that with the expansion of performance measurement can be expected to improve the ability of the nursing staff in the business area and generate healthy competitive rivalry.