Aim:To determine self-efficacy perception of nurses about computers. Method:The Study was conducted on 290 out of 524 working nurses at a university in a hospital. Results: 99% of the nurses told that they could use computer and internet, 79% of them had personal computers. Nurses got a total score of 35.56±8.08 from CSES. It was determined that there was a negative and weak correlation between nurses' age and total scale score while there was a statistically significant, negative and moderate correlation between total scale score and their professional experience and hospital experience. There were statistically significant differences in the fact that single nurses had higher scale scores than married nurses, male nurses than female nurses, those who had a bachelor's degree and health high school degree than those who had an associate degree and those who had personal computer than those who did not. Conclusion: Most of the nurses who knew how to use the computer, had e-mail addresses and computers in their homes. However, while the computer-related self-sufficiency perception of nurses was at medium level, the same perception in nurses who were male, single had bachelor's degree and health high school degree with younger ages and less professional experience was higher.