Applying the proper 5S(sort, set, shine, standardize and sustain) is essential to maximize the level of occupational safety and health that can be associated with the increasing of productivity. This research aims to analyzed the in- fluence of work periods and knowledge of 5S to the 5S implementation at the logistics section in heavy equipment fabrication company Gresik. This study used secondary data from a previous study in heavy equipment fabrication company in the logistics section. The research is an analytical study which has a purpose to evaluate the influence between work periods and knowledge of 5S to the 5S implementation. Statistical analysis uses linear regression with 1000 replication bootstrap with small sample size (24 samples). The most distribution of employee According to thework period in the logistics section in heavy equipment fabrication company Gresik is <6 years, knowledge of 5S as 100% included in the good category, and 5S implementation as many as 100% included in the good category. There was no effect of work periods on the implementation of 5S and there was an influence of the knowledge of 5S on the implementation of 5S.