Introduction: Tooth wear is the non-carious loss of tooth structure. One of the types of tooth wear is attrition. The attrition results from tooth to tooth contact (occlusion) such as during mastication. There are three types of occlusion during lateral movement of the mandible are balanced occlusion, group function, and cuspid protected. The purpose of this study was to identify the relationship between balanced occlusion, group function, and cuspid protected with the tooth wear and to identify the type of occlusion which is the most causing the tooth wear. Methods: This research is observational analysis using cross-sectional study. The subjects are 78 preclinical dental students from the University of Indonesia Class 2005-2008, aged 17-23 years old which were taken by purposive sampling. Univariate statistical analysis is the distribution of each variable and bivariate statistical analysis is using Fisher test. Results: Fisher test showed that there was no relationship between balanced occlusion, group function, and cuspid protected with the tooth wear (p > 0,05). Descriptive statistic was not been able to prove the type of occlusion which is the most causing the tooth wear. Conclusion: There was no relationship between balanced occlusion, group function, and cuspid protected with tooth wear on preclinical dental student from University of Indonesia Class 2005-2008. And, there is no evidence that balanced occlusion is the most causing the tooth wear.