Introduction: Oral lichen planus (OLP) is a chronic autoimmune disease of unknown etiology mediated by T cells. The clinical lesion of OLP is almost similar to oral lichenoid lesions (OLL). OLL and OLP can be distinguished from the presence of precipitating factors. OLP and OLL may occur in association with xerostomia. The triad of oral lichen planus, diabetes mellitus, and hypertension can be referred as Grinspan’s syndrome. The objective of this study was to determine the difference between oral lichen planus or oral lichenoid reaction from the clinical features. Manage-ment: The right diagnosis can determine the best treatment for patients, in which laboratory tests and salivary flow rate checks are performed. Conclusion: A geriatric patient is diagnosed with OLP, in which it is proven by her clinical features and factors associated with OLP lesions referred to be diabetes mellitus and hypertension (Grinspan’s syn-drome). Dentist has important roles in the diagnosis and treatment of oral conditions associated with both of these diseases.