Introduction: Biomedical engineering is a rapidly growing discipline covering the application of engineering princi-ples and materials technology to healthcare. Nowdays, nanotechnology based drug carrier or regenerative medicine are developed. Nanotechnologies have the potential to improve diagnosis or therapeutical applications. Nanopar-ticle materials can be found from natural source or synthetic source. Hydroxyapatyte has been commonly used in dentistry because of the characteristic. But, hydroxyapatyte has some disadvantages such as low tensile stength and brittleness. It is desirable to make smaller particle of hydroxyapatyte. Nano- hydroxyapatite (n-HAp) is considered one of the most biocompatible materials. In this study, we discuss the synthesis of nanohydroxyapatyte using elec-trochemical method and describe the surface morphology with scanning electron microscopy. Method: KH2PO4, Na2EDTA, CaCl2 was dissolve with demineralized water. The electrolysis was carried out in two platinum foil electrodes were connected to the positive and negative terminals of a DC power supply. Result: There was highly agglomerated of nanohydroxyapatite. The spherical shaped particles with clumped distributions. Conclusion: Sur-face morphology of nanohydroxyapatyte that synthesize using electrochemical method was highly agglomerated.