Introduction: Teledentistry is an application that provide dental care, consultation, treatment plan and follow up in real time or offline through electronic transmission from distant location. This article objective is to review systemat-ically about the use of teledentistry in Oral Medicine field in order to enhance diagnosis difficulties. Method: Elec-tronic databases were searched to find relevant articles, limited in English language and publication for the period of March 2009 up to March 2019. Literature searches were conducted from relevant databases. The search strategy included subject and keyword searching. Result: Of 100 possible articles that were seen, only 7 articles that meet the inclusion criteria. The studies showed that teledentistry in oral medicine field can reach remote areas, such as in countries with vast areas with lack of dentists, such as Australia and Brazil. Most of the studies uses smartphone application in performing teledentistry. Conclusions: Teledentistry has been used in Oral Medicine field, in the form of consultation, clinical examination, diagnosis ability for oral lesions and oral medicine referral. The lack of corre-sponding studies in this systematic reviews, showed the further need to elaborate more of teledentistry usefulness in Oral Medicine.