Introduction:Periodontitis is an inflammatory reaction caused by specific microorganisms that cause damage to the alveolar bone. The bacteria can cause a severe damage, and one of them is known as Aggregatibacter actinomyce-temcomitans. Bone damage can be caused of osteoclast activity. Osteoclast biomarker in blood serum was named a Crosslink C-Terminal Telopeptide (CTx). Green tea (Camellia sinensis) contains active ingredient epigallocatechin gallate (EGCG) which was proven to regenerate bone by increasing bone cell proliferation and differentiation using periodontitis wistar rats. Methods: This study was divided into 4 groups: The first group was a negative control, the second was a positive control, the third and the fourth were treatment groups. The negative control group did not receive any treatment. The positive control group was given LPS Aa 5 μg/3μl PBS and Camellia sinensis induction with each dose 150 mg / 100 grBB and 200 mg / 100 grBB on days 21-36 days. The level of CTx was examined by using ELISA method to observe osteoclast activity. The number of osteoclast were stained by HE method. Results: data analysis showed there was a very strong correlation between administration of Camellia sinensis extract and an increase in osteocyte count (p <0.05, with correlation coefficient = 0.883), whereas CTx levels showed that there were no significantly different (p>0,05) between positive groups with treatment caches one and two. Conclusion:This study revealed that was a Camellia sinensis could increase the number of osteocytes in periodontitis inducing LPS Aa on rat wistar.