View Article |
Intraocular pressure: the effect of short-term fasting and its association with fluid and fat status
Nur Raihan Esa1, Nor Azwani Mohd Shukri2, Norsham Ahmad3, Mohd Radzi Hilmi4, Md Muziman Syah Md Mustafa5, Nura Syahiera Ibrahim6, Fatin Amalina Che Arif7, Firdaus Yusof @Alias8.
Introduction: Short-term fasting may influence intraocular pressure (IOP) due to alteration of fluid (total body water;
TBW, and water intake) and fat (total body fat; TBF). This study aimed: i) to compare IOP values within and between,
fasting and non-fasting periods; and ii) to assess the association between IOP and, TBW and TBF. Methods: Thirty
healthy participants aged 21.8±1.1 years were assessed on two different periods (fasting vs. non-fasting). During each
period, the IOP, TBW and TBF values were assessed for four times (morning, afternoon, evening, late-evening). The
IOP was measured using AccuPen® tonopen, while TBW and TBF were assessed by using a Tanita body composition
analyser. Results: During fasting, the IOP value in the afternoon (14.53±2.33 mmHg) was significantly higher than in
the evening (12.43±2.73 mmHg, p=0.009) and late-evening (12.60±2.44 mmHg, p=0.003). No significant difference
in IOP was observed during non-fasting period. The mean of IOP in the evening was significantly lower during fasting
compared to non-fasting (12.43±2.73 mmHg vs 13.75±2.53 mmHg, p=0.044). The IOP and TBW were negatively
correlated (r=-0.268; p=0.011) during non-fasting and showed no association during fasting period. There was no
significant correlation between IOP and TBF during both fasting and non-fasting periods. Conclusion: IOP reduction
during short-term fasting, together with the no association with TBF and TBW suggested that IOP is an independent
factor that reduces during fasting in healthy population.
Affiliation:
- International Islamic University Malaysia, Malaysia
- International Islamic University Malaysia, Malaysia
- International Islamic University Malaysia, Malaysia
- International Islamic University Malaysia, Malaysia
- International Islamic University Malaysia, Malaysia
- International Islamic University Malaysia, Malaysia
- International Islamic University Malaysia, Malaysia
- International Islamic University Malaysia, Malaysia
|
|
Indexation |
Indexed by |
MyJurnal (2021) |
H-Index
|
3 |
Immediacy Index
|
0.000 |
Rank |
0 |
Indexed by |
Scopus 2020 |
Impact Factor
|
CiteScore (0.2) |
Rank |
Q4 (Medicine (all)) |
Additional Information |
SJR (0.144) |
|
|
|