This study x-ray business communication skills acquisition required by entrepreneurs for sustainable development in Oyo State, Nigeria. Four (4) research questions guided the study. A survey design was adopted. The population was 2600 entrepreneurs registered with Nigerian Chamber of Commerce, Industry, Mines and Agriculture (NACCIIMA) in Oyo State while 10% totalling 260 respondents were randomly selected using simple random sampling techniques formed the sample size for this study. A-35 item structured questionnaire validated by 4 experts was used for data collection. The pilot study conducted yielded a reliability coefficient of 0.78 which was high enough for the instrument to be considered reliable. Mean and the standard deviation was used to analyze the findings. The findings revealed among others that listening and speaking communication skills are highly required by entrepreneurs for sustainable development. Based on the findings, it was recommended among others that in house training should be conducted for entrepreneurs to address communication skill gap for sustainable development.