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Necrotizing autoimmune myopathy: a case series
Narisa Sulaiman Sahari1, Abdul Aziz Marwan2, Dayang Masyrinartie Suahilai3, Nurulraziquin Mohd Jamid4, Nor Shuhaila Shahril5.
Necrotizing autoimmune myopathy (NAM) is considered a new subgroup of a rare autoimmune idiopathic inflam- matory myopathies. Classically, NAM presented with sub-acute onset of proximal muscle loss of power with raised creatinine kinase and characteristic muscle biopsy showing muscle necrosis and regeneration with little inflamma- tion. Statin use, connective tissue diseases, malignancy and HIV infection are the identified risk factors for NAM. The autoantibodies expected to be presented in NAM are anti-signal recognition particle (SRP) and anti-hydroxymethylgl- utaryl-coenzyme A reductase (anti-HMGCR) antibodies. In this article, we present three cases of NAM with different risk factors and autoantibodies which we believe to have impact on the clinical course and outcome of our patients
Affiliation:
- Universiti Putra Malaysia, Malaysia
- Universiti Sains Islam Malaysia, Malaysia
- Hospital Putrajaya, Malaysia
- Hospital Putrajaya, Malaysia
- Hospital Putrajaya, Malaysia
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Indexation |
Indexed by |
MyJurnal (2021) |
H-Index
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3 |
Immediacy Index
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0.000 |
Rank |
0 |
Indexed by |
Scopus 2020 |
Impact Factor
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CiteScore (0.2) |
Rank |
Q4 (Medicine (all)) |
Additional Information |
SJR (0.144) |
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