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Correlation Between Ferritin and Thyroid Hormones in Obesity
Meita Hendrianingtyas1, Satrio Adi Wicaksono22, Lydia Purna Widyastuti Setjadiningrat Kuntjoro3, Maharani4, Sulistiyati Bayu Utami25.
Introduction: Obesity is one of the risk factors for various metabolic diseases that will cause various kinds of
complications. Continuous sub-acute chronic inflammation is characterized by increased inflammatory markers,
one of which is ferritin. Low iron that can be detected with ferritin, may alter thyroid metabolism. Chronic
inflammatory conditions can cause disruption of thyroid hormone production. The purpose of this study was to
examine the correlation between ferritin levels and thyroid hormone levels in obese populations.
Methods: This was a cross-sectional study enroling 41 subjects with obesity with BMI >27 in Diponegoro
National Hospital Semarang. Thyroid hormone levels (TSH, T3, FT3, T4 and FT4) and ferritin were examined
with an immunology analyzer. Spearman correlation test was performed. p<0.05 was considered as
statistically significant. Results: There were significant weak positive correlations between ferritin levels with T3
(r=0.38; p=0.02) and with FT3 levels (r=0.33; p=0.05). There were no correlations between ferritin levels with
TSH, T4, and FT4. Conclusion: Ferritin levels might have association with T3 and FT3 levels in obese population.
If confirmed by further studies, ferritin and thyroid hormones levels could be used in therapeutic monitoring
in obese population.
Affiliation:
- Diponegoro University, Semarang, Indonesia
- Diponegoro National Hospital, Prof Soedharto, Tembalang, Semarang, 50275, Indonesia, Indonesia
- Diponegoro National Hospital, Prof Soedharto, Tembalang, Semarang, 50275, Indonesia, Indonesia
- Diponegoro National Hospital, Prof Soedharto, Tembalang, Semarang, 50275, Indonesia, Indonesia
- Diponegoro National Hospital, Prof Soedharto, Tembalang, Semarang, 50275, Indonesia, Indonesia
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Indexation |
Indexed by |
MyJurnal (2021) |
H-Index
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3 |
Immediacy Index
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0.000 |
Rank |
0 |
Indexed by |
Scopus 2020 |
Impact Factor
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CiteScore (0.2) |
Rank |
Q4 (Medicine (all)) |
Additional Information |
SJR (0.144) |
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