Introduction: Hypertension in pregnancy is one of the greatest causes of maternal mortality in Jepara, a coastal area with great fish production. Seafood intake in pregnancy is considered has a beneficial effect on reducing blood pressure due to its EPA and DHA content. However, its consumption is also considered to increase blood pressure because of sodium content. This research is aimed to investigate the effect of seafood intake on blood pressure of pregnant women in coastal area in Jepara Indonesia. Methods: This research was a cross-sectional study was conducted among 105 of 175 pregnant women that had been living in coastal area in Jepara for at least a month during pregnancy. Each participant was interviewed about their seafood and other food intake during pregnancy. The blood pressure was examined using sphygmomanometer. Seafood intake was categorized as low to normal (≤12 ounces a week) and high (>12 ounces a week). Pregnant women who had smoking habit, hypertension history, and seafood allergy were excluded. Results: Most pregnant women in coastal area Jepara had high seafood intake which was more than 12 ounces or 340.2 grams a week. Normal blood pressure was found in 94 pregnant women (89.5%). High seafood intake shown a significant association on lowering blood pressure. (p<0.05; Chi Square test). Conclusion: Seafood intake is associated to blood pressure levels in coastal pregnant women. Further research about nutrition content in seafood and recommendation seafood consumed by pregnant women is needed.