The present study aims at analyzing the effect of chewable tobacco on the in-vitro wear measurements of two dental composite materials. In this test, the pins were made up of dental composites: micro-filled Z250 and nano-filled Z350 translucent shade and immersed in tobacco solution. In-vitro measurements were conducted on a pin-on-disk tribometer in the presence of artificial saliva at three different loading conditions with a constant disc speed. Three specimens of each composite material were produced, and six readings were recorded by using both sides of pin specimens to observe the tribological behaviour. The microstructures of the pin surfaces were inspected by using scanning electron microscopy (SEM). At initial stages i.e. just a few days after immersion, there was less change in the wear measurement for both the materials. Significant changes were observed after one month. Specimens prepared with nano-filled Z350 material showed smooth wear features whereas micro-filled Z250 progressively articulated wear details were observed with a chewable tobacco environment. The wear measurements of tested dental material specimens were influenced by tobacco immersion. The nano-filled Z350 translucent material exhibits less wear as compared to micro-filled Z250 material.