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Effects of using two different dosing of propofol as an induction agent in patients undergoing Electro Convulsive Therapy (ECT) at the psychiatric department, Hospital Kuala Lumpur
Mohamad Nor1, Zarina Awang2, Zarina Kasim3.
Introduction: Electroconvulsive therapy (ECT) is one of the treatments in treating psychotic disorders. Indications for ECT are major depressive disorder, bipolar mood disorder, and schizophrenia. Propofol reduces the seizure activity for those patients who underwent the ECT. Still, considering the dose of propofol given by using a lower dosage of propofol based on recommended doses, it might increase seizure activity quality without harmful effects on the patients. Methods: A retrospective study was conducted to evaluate the seizure duration, quality of EEG, postictal suppression, and recovery time in 200 patients undergoing ECT treatment who were sedated with either low dose (<1.5 mg/kg) or high dose (> 1.5 mg/kg) of propofol at Psychiatric Department, Hospital Kuala Lumpur between June 2016 to June 2017. All the results were analyzed with the statistical software SPSS (v. 22.0). Results: Based on the finding in this study, the group of who received propofol at less than 1.5 mg/kg tend to get longer seizure motor du- ration compared to the group of more than 1.5 mg/kg. The result showed the mean duration of motor seizure in the group at less than 1.5 mg/kg of propofol is significantly higher than the group of more than 1.5 mg/kg. Conclusions: Thus, it is essential to titrate propofol using propofol towards the patients undergoing the ECT procedure and using a lower dose of propofol.
Affiliation:
- Hospital Sultanah Aminah, Johor Bharu, 80100, Johor Bharu, Malaysia
- Hospital Kuala Lumpur, 50586, Kuala Lumpur, Malaysia
- Lincoln University College, Wisma Lincoln, no. 12-18 Off Jalan Perbandaran, 47301 Petaling Jaya, Selangor D. E, Malaysia
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Indexation |
Indexed by |
MyJurnal (2021) |
H-Index
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3 |
Immediacy Index
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0.000 |
Rank |
0 |
Indexed by |
Scopus 2020 |
Impact Factor
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CiteScore (0.2) |
Rank |
Q4 (Medicine (all)) |
Additional Information |
SJR (0.144) |
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