Introduction: Online health education was the norm to maintain physical distancing during this pandemic era (2020- 2021). Furthermore, the generation 5.0 in this era prefers online communication since they needed to stay at home. On account of these issues, this study aimed to investigate an online health education module on healthy diets and regular exercises in achieving a health related quality of life. Methods: A total of 301 respondents were enrolled. The RAND SF-36 survey questionnaire was used for pre- and post-testing the eight domains of the health related quality of life. The online health education on healthy diets and regular exercises as the intervention were investigated in three phases where all phases were completed in 12 months minimum. Results: The eight domains of the health related quality of life (pï‚£0.05) was achieved. Specifically, the general health (72.700±41.1, p0.00915), physical functioning (82.3200±51.8, p0.0015), role physical (92.02±41.06, p0.001), role emotional (72.706±21.12, p0.00), social functioning (96.09±48.727, p0.0012), bodily pain (99.3±69.128, p0.015), vitality (62.7±31.08, p0.0104), and mental health (72.35±41.18, p0.00455) were achieved. Conclusion: Using an online module for healthy diets (70.56 ± 20.93391, 210%) and regular exercises (78.44 ± 18.85421, 188%) as a strategic intervention was effective (pï‚£0.05) during this pandemic era.