Prosthodontists face a challenge when treating a maxillary defect caused by a tumor, trauma, or congenital deforma- tion. With the help of maxillofacial restoration, the defect can be restored to near normal function and appearance. The goal of maxillectomy prosthesis rehabilitation is to separate the oral cavity and the nasal cavity to allow adequate swallowing and biting, thus restoring the contour of the midface and providing acceptable results. A thirteen-year- old boy presented with swelling on the right side of his face. The swelling began eight months prior and gradually worsened. Facial asymmetry was discovered due to swelling of the right buccal region, which was soft, painless, and covered by normal skin. The overgrowth can be seen on intraoral examination of the right posterior area of the maxilla, extending from the distal side of 14 to the mesial area of 17. The multidisciplinary approach of the head and neck surgeon, ophthalmologist, and prosthodontist is used to make decisions for definitive treatment planning. The immediate obturator is made and adjusted before the operation to accommodate the defect during the operation. Three weeks later, an interim obturator was fabricated. In maxillary resection patients, obturator prosthesis helps to improve speech intelligibility, good maxillofacial appearance, better chewing, convenience and social interaction.