Cloud Computing offers variant services through the Internet that benefit Small and Medium Business (SMB). Even though cloud computing technology providers offer various cloud services, there are existing challenges in cloud computing adoption. The most crucial challenges are related to system migration and security concern subjects in cloud-based environments. Thus, this study carried out a systematic literature review since it uses a more rigorous and well-defined method to find the challenges factors of cloud computing adoption to SMB companies in Malaysia. The conclusive findings of the study suggest that cloud computing can increase business agility and values and promote a competitive business for SMBs while neutralized its challenges. This study aims to propose a cloud computing adoption based on TAM/TOE model. The results will assist Chief Information Security Officer (CISO), I.T. Manager, Chief Technology and Information Officers representing the SMBs.