Background: The ramifications of immobilisation manifest in a spectrum of physical and mental complications across participants demographics, irrespective of age. The resultant challenges impede individuals from independently executing routine activities, such as bathing and mobility. Consequently, there is an escalating demand for nursing care to assist participants, while concurrently, meeting these needs becomes progressively challenging. This study aims to explore the needs of orthopaedic Muslim participants during their period of immobilisation. Methods: This qualitative investigation adopted a semi-structured interview approach to engage participants, specifically Muslim orthopaedic participants at the Orthopaedic Ward of Sultan Haji Ahmad Shah Medical Centre @IIUM (SASMEC@IIUM). The study encompassed interviews with 10 participants, each experiencing immobilisation due to varying reasons and for differing durations. The interviews aimed to discern the participants' needs, Islamic practices observed during immobilisation, and their satisfaction levels regarding received nursing care. Results: The study's findings elucidated multifaceted needs encompassing physical, psychological, psychosocial, financial aspects, pain management during immobilisation, Islamic practices, and nursing care satisfaction. Immobilisation profoundly affects participants across physical, psychological, psychosocial, and religious dimensions, necessitating support from individuals, aid from specialized equipment, communal assistance, the application of Rukhsah (Islamic dispensation), and tailored nursing care. Conclusion: High-quality care from both nurses and family members is imperative to adequately address the myriad needs of immobilized participants. Enhanced support and attentive care significantly mitigate the risk of complications in participants recovery.