Infective meningoencephalitis: recent advances in management of japanese b encephalitis in the ASEAN region
Pancharoen, C1, Thisyakorn, U2.
Japanese encephalitis (JE) is a flaviviral infection of the central nervous system. The virus (JEV) is transmitted to man through mosquito bites. JE has long been endemic in South and Southeast Asia and the Western Pacific regions. It is a zoonotic disease, infecting man as an incidental host. The ratio of overt disease to inapparent infection varies from 1:300 to 1:1 000. Culicine mosquitoes, notably Culex tritaeniorhynchus, are the main vector. Rice fields are their principal breeding place and pigs are important amplifying hosts. Other vertebrate hosts include bovines, horses and possibly birds. Most JE patients come from areas where there are rice fields and pigs. In countries where JE has been present for many years, annual peaks of cycles have been irregular.
Affiliation:
- Chulalongkorn University, Thailand
- Chulalongkorn University, Thailand
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