The current study explores the energetic process with the help of human resources practices (Compensation, psychological empowerment practices and supervision) in the university which control the job satisfaction over the timing. A cross section research was done with the help questionnaire, which consists of 33 items and which was distributed among 120 employees of the selected university lectures, assistant professors and associate professor. SPSS 18 is used to analysis the data and it was found that every HR (Compensation, psychological empowerment practices and supervision) practices have a significant relationships with job satisfaction. It also identifies the relationship between these in the perspectives of Pakistan.