Developing applications using Multi Modal Human Computer Interaction (MMHCI) remains a great challenge due to the advancement of technologies. Enhanced interaction applications and tools employed in medical records will help to improve the quality of patients’ healthcare and it opens a variety of research challenges. Replacing a difficult system to store complex data related to medical history of patients through Electronic Medical Records (EMR)/Electronic Health Records (EHR) would offer several advantages that include confidentiality and patient details reliability along with the mechanisms for quick and flexible retrieval of data/information. The task of designing MMHCI applications for real time environment for EMR/EHR is thus complex. As the inputs to medical systems are heterogeneous, the associated issues grow up with the need for new system since the existing frameworks have many gaps and drawbacks. This paper attempts to discuss the possible guidelines, standards, tools and techniques involved in integrating MMHCI with EMR/EHR.