In this work, the hydrogen production during biomass steam pyrolysis-gasification with a combined catalysts and sorbent. The biomass sample was originated from sugarcane leaves. The combined catalyst and sorbent (NiO-MgO-CaO/γ-Al2O3) was prepared by an excess-solution impregnation method and the property of fresh and used catalysts was characterized using XRD. The prepared sorbent-catalysts promoted both tar reforming and CO2 absorption. High hydrogen production was achieved due to the enhanced water–gas shift reaction by the latter. The pyrolysis-gasification experiments were conducted in a drop tube two-stage fixed bed reactor. The effect of operating parameters such as the amount of MgO (3, 5 and 10 wt.%) and CaO (3, 5 and 10 wt.%) on supported catalysts and the gasification temperatures (600, 700 and 800 oC) were investigated. It was found that the highest hydrogen yield of 23.2 mmol H2/gbiomass was attained using the Ni10Mg5Ca5 catalyst at the gasification temperature of 600 oC. However, the maximum of tar conversion was observed around 78 wt.% at gasification temperature up to 800 oC.